E88.A
Wasting disease (syndrome) due to underlying condition
E88.A (also written E88A) is a billable ICD-10-CM diagnosis code for wasting disease (syndrome) due to underlying condition. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 24 codes in category E88 (Other and unspecified metabolic disorders). The Alphabetic Index lists it under 7 entries. Its coding notes include a Code first instruction, a Use additional code instruction, 9 Excludes1 entries and 2 Excludes2 entries.
Code first
If the underlying condition listed here is present and known, sequence it first.
- underlying condition
Use additional code
Add the listed code as a secondary code, if known.
- codes for associated conditions
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Also from chapter/block level (6 notes)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Hospice: not accepted as primary
Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Supplementary or additional code, not allowed as principal diagnosis.
Inclusion terms
Conditions classified to this code.
- Cachexia due to underlying condition
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 7 entries