E29.1
Testicular hypofunction
E29.1 (also written E291) is a billable ICD-10-CM diagnosis code for testicular hypofunction. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 4 codes in category E29 (Testicular dysfunction). The Alphabetic Index lists it under 18 entries. Its coding notes include a Use additional code instruction and 8 Excludes1 entries.
Use additional code
Add the listed code as a secondary code, if known.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- postprocedural testicular hypofunction (E89.5)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Endocrine clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Defective biosynthesis of testicular androgen NOS
- 5-Alpha-reductase deficiency (with male pseudohermaphroditism)
- Testicular hypogonadism NOS
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 18 entries
- Abnormal, abnormality, abnormalities, biosynthesis, testicular androgen
- Defect, defective, biosynthesis, androgen (testicular)
- Deficiency, deficient, 5-alpha reductase (with male pseudohermaphroditism)
- Deficiency, deficient, hormone, testicular
- Eunuchoidism
- Failure, failed, Leydig's cell, adult
- Failure, failed, seminiferous tubule, adult
- Failure, failed, testicular endocrine function
- Hypofunction, testicular
- Hypogonadism, male
- Hypogonadism, testicular (primary)
- Infantile, testis