E88
Other and unspecified metabolic disorders
E88 is a non-billable ICD-10-CM code category for other and unspecified metabolic disorders. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are E88.0 Disorders of plasma-protein metabolism, not elsewhere classified; E88.1 Lipodystrophy, not elsewhere classified; E88.2 Lipomatosis, not elsewhere classified; E88.3 Tumor lysis syndrome and 4 more. Its coding notes include a Use additional code instruction, 7 Excludes1 entries and 1 Excludes2 entry.
Use additional code
Add the listed code as a secondary code, if known.
- codes for associated conditions
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- histiocytosis X (chronic) (C96.6)
Also from chapter/block level (6 notes)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
More specific codes under E88 8
- E88.0Disorders of plasma-protein metabolism, not elsewhere classifiedHeader
- E88.1Lipodystrophy, not elsewhere classifiedHeader
- E88.2Lipomatosis, not elsewhere classifiedBillable
- E88.3Tumor lysis syndromeBillable
- E88.4Mitochondrial metabolism disordersHeader
- E88.8Other specified metabolic disordersHeader
- E88.9Metabolic disorder, unspecifiedBillable
- E88.AWasting disease (syndrome) due to underlying conditionBillable