E88.0
Disorders of plasma-protein metabolism, not elsewhere classified
E88.0 is a non-billable ICD-10-CM code header for disorders of plasma-protein metabolism, not elsewhere classified. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are E88.01 Alpha-1-antitrypsin deficiency; E88.02 Plasminogen deficiency and E88.09 Other disorders of plasma-protein metabolism, not elsewhere classified. Its coding notes include a Use additional code instruction, 10 Excludes1 entries and 2 Excludes2 entries.
Use additional code
Add the listed code as a secondary code, if known.
- codes for associated conditions
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Also from chapter/block level (6 notes)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- disorder of lipoprotein metabolism (E78.-)
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.