E79

Disorders of purine and pyrimidine metabolism

FY2027Chapter 4: Endocrine, nutritional and metabolic diseases/E70–E88 Metabolic disorders

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

Excludes1
Excludes2

E79 is a non-billable ICD-10-CM code category for disorders of purine and pyrimidine metabolism. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are E79.0 Hyperuricemia without signs of inflammatory arthritis and tophaceous disease, E79.1 Lesch-Nyhan syndrome, E79.2 Myoadenylate deaminase deficiency, E79.8 Other disorders of purine and pyrimidine metabolism and 1 more. Its coding notes include 17 Excludes1 entries and 1 Excludes2 entry.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code

Ataxia-telangiectasia (Q87.19)
Bloom's syndrome (Q82.8)
Cockayne's syndrome (Q87.19)
calculus of kidney (N20.0)
combined immunodeficiency disorders (D81.-)
Fanconi's anemia (D61.09)
gout (M1A.-, M10.-)
orotaciduric anemia (D53.0)
progeria (E34.8)
Werner's syndrome (E34.8)
xeroderma pigmentosum (Q82.1)

Also from chapter/block level (6 notes)

Inherited from E70–E88 Metabolic disorders

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (1 note)

Inherited from E70–E88 Metabolic disorders

Ehlers-Danlos syndromes (Q79.6-)

Notes

Also from chapter/block level (1 note)

Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

More specific codes under E79 5