E72.9
Disorder of amino-acid metabolism, unspecified
E72.9 (also written E729) is a billable ICD-10-CM diagnosis code for disorder of amino-acid metabolism, unspecified. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 31 codes in category E72 (Other disorders of amino-acid metabolism). The Alphabetic Index lists it under 6 entries. Its coding notes include 12 Excludes1 entries and 1 Excludes2 entry.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Also from chapter/block level (6 notes)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 140 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CNotes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 6 entries