D59.39
Other hemolytic-uremic syndrome
D59.39 (also written D5939) is a billable ICD-10-CM diagnosis code for other hemolytic-uremic syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 16 codes in category D59 (Acquired hemolytic anemia). The Alphabetic Index lists it under 5 entries. Its coding notes include a Code first instruction, a Use additional code instruction, a Code also instruction and 9 Excludes2 entries.
Code first
If the underlying condition listed here is present and known, sequence it first.
Use additional code
Add the listed code as a secondary code, if known.
- code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)
Code also
Two codes may be needed to describe the condition. This note gives no sequencing order.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Hospital MCC
Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 110 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CInclusion terms
Conditions classified to this code.
- Atypical (nongenetic) hemolytic uremic syndrome
- Secondary hemolytic-uremic syndrome
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 5 entries