D59.3

Hemolytic-uremic syndrome

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D55–D59 Hemolytic anemias

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

D59.3 is a non-billable ICD-10-CM code header for hemolytic-uremic syndrome. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D59.30 Hemolytic-uremic syndrome, unspecified; D59.31 Infection-associated hemolytic-uremic syndrome; D59.32 Hereditary hemolytic-uremic syndrome and D59.39 Other hemolytic-uremic syndrome. Its coding notes include a Code also instruction and 9 Excludes2 entries.

Code also

Two codes may be needed to describe the condition. This note gives no sequencing order.

This code
  • , if applicable, any associated:
    • acute kidney failure (N17.-)
    • chronic kidney disease (N18.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes under D59.3 4