D59.32

Hereditary hemolytic-uremic syndrome

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D55–D59 Hemolytic anemias

BillableComplete code, valid to report

D59.32 (also written D5932) is a billable ICD-10-CM diagnosis code for hereditary hemolytic-uremic syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 16 codes in category D59 (Acquired hemolytic anemia). The Alphabetic Index lists it under 5 entries. Its coding notes include a Code also instruction and 9 Excludes2 entries.

Code also

Two codes may be needed to describe the condition. This note gives no sequencing order.

This code
  • , if applicable:
    • defects in the complement system (D84.1)
    • methylmalonic acidemia (E71.120)
Inherited from D59.3 Hemolytic-uremic syndrome
  • , if applicable, any associated:
    • acute kidney failure (N17.-)
    • chronic kidney disease (N18.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital MCC

Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 110 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Inclusion terms

Conditions classified to this code.

This code
  • Atypical hemolytic uremic syndrome with an identified genetic cause

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 5 entries