D61.811

Other drug-induced pancytopenia

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D60–D64 Aplastic and other anemias and other bone marrow failure syndromes

BillableComplete code, valid to report

D61.811 (also written D61811) is a billable ICD-10-CM diagnosis code for other drug-induced pancytopenia. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 13 codes in category D61 (Other aplastic anemias and other bone marrow failure syndromes). The Alphabetic Index lists it under 1 entry. Its coding notes include 7 Excludes1 entries and 12 Excludes2 entries.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from D61.81 Pancytopenia
  • pancytopenia (due to) (with) aplastic anemia (D61.9)
  • pancytopenia (due to) (with) bone marrow infiltration (D61.82)
  • pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
  • pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
  • pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
  • pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
  • pancytopenia (due to) (with) myeloproliferative disease (D47.1)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

This code
  • aplastic anemia due to drugs (D61.1)
Inherited from D61.81 Pancytopenia
  • pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)
Inherited from D61 Other aplastic anemias and other bone marrow failure syndromes
Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital MCC

Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 41 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry