D61.1
Drug-induced aplastic anemia
D61.1 (also written D611) is a billable ICD-10-CM diagnosis code for drug-induced aplastic anemia. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 13 codes in category D61 (Other aplastic anemias and other bone marrow failure syndromes). The Alphabetic Index lists it under 2 entries. Its coding notes include a Use additional code instruction and 10 Excludes2 entries.
Use additional code
Add the listed code as a secondary code, if known.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- neutropenia (D70.-)
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Hospital MCC
Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 110 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CAlphabetic Index terms
Terms the official Alphabetic Index lists for this code. 2 entries