D61.2
Aplastic anemia due to other external agents
D61.2 (also written D612) is a billable ICD-10-CM diagnosis code for aplastic anemia due to other external agents. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 13 codes in category D61 (Other aplastic anemias and other bone marrow failure syndromes). The Alphabetic Index lists it under 5 entries. Its coding notes include a Code first instruction and 10 Excludes2 entries.
Code first
If the underlying condition listed here is present and known, sequence it first.
- , if applicable, toxic effects of substances chiefly nonmedicinal as to source (T51-T65)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- neutropenia (D70.-)
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Hospital MCC
Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 110 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CAlphabetic Index terms
Terms the official Alphabetic Index lists for this code. 5 entries
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), aplastic, due to, external agents NEC
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), aplastic, due to, infection
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), aplastic, due to, radiation
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), aplastic, toxic
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), toxic