D61.81
Pancytopenia
Non-billable headerNot valid on its own. Use one of the more specific codes under it.
D61.81 is a non-billable ICD-10-CM code header for pancytopenia. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D61.810 Antineoplastic chemotherapy induced pancytopenia, D61.811 Other drug-induced pancytopenia and D61.818 Other pancytopenia. Its coding notes include 7 Excludes1 entries and 11 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
This code
- pancytopenia (due to) (with) aplastic anemia (D61.9)
- pancytopenia (due to) (with) bone marrow infiltration (D61.82)
- pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
- pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
- pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
- pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
- pancytopenia (due to) (with) myeloproliferative disease (D47.1)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
This code
- pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)
Inherited from D61 Other aplastic anemias and other bone marrow failure syndromes
- neutropenia (D70.-)
Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)