D89.811

Chronic graft-versus-host disease

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D80–D89 Certain disorders involving the immune mechanism

BillableComplete code, valid to report

D89.811 (also written D89811) is a billable ICD-10-CM diagnosis code for chronic graft-versus-host disease. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 24 codes in category D89 (Other disorders involving the immune mechanism, not elsewhere classified). The Alphabetic Index lists it under 3 entries. Its coding notes include a Code first instruction, a Use additional code instruction, 4 Excludes1 entries and 11 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

Inherited from D89.81 Graft-versus-host disease
  • underlying cause, such as:
    • complications of transplanted organs and tissue (T86.-)
    • complications of blood transfusion (T80.89)

Use additional code

Add the listed code as a secondary code, if known.

Inherited from D89.81 Graft-versus-host disease
  • code to identify associated manifestations, such as:

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from D89 Other disorders involving the immune mechanism, not elsewhere classified
  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)
Also from chapter/block level (2 notes)
Inherited from D80–D89 Certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from D89 Other disorders involving the immune mechanism, not elsewhere classified
  • transplant failure and rejection (T86.-)
Also from chapter/block level (10 notes)
Inherited from D80–D89 Certain disorders involving the immune mechanism
  • human immunodeficiency virus [HIV] disease (B20)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospice: not accepted as primary

Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Supplementary or additional code, not allowed as principal diagnosis.

Source: CMS Integrated Outpatient Code Editor (IOCE) v27.3, effective October 1, 2026, edit 113

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 47 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Includes

Further defines or gives examples of the content of the category.

Also from chapter/block level (3 notes)
Inherited from D80–D89 Certain disorders involving the immune mechanism
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 3 entries