D89.81
Graft-versus-host disease
D89.81 is a non-billable ICD-10-CM code header for graft-versus-host disease. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D89.810 Acute graft-versus-host disease; D89.811 Chronic graft-versus-host disease; D89.812 Acute on chronic graft-versus-host disease and D89.813 Graft-versus-host disease, unspecified. Its coding notes include a Code first instruction, a Use additional code instruction, 4 Excludes1 entries and 11 Excludes2 entries.
Code first
If the underlying condition listed here is present and known, sequence it first.
Use additional code
Add the listed code as a secondary code, if known.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- transplant failure and rejection (T86.-)
Also from chapter/block level (10 notes)
- human immunodeficiency virus [HIV] disease (B20)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Includes
Further defines or gives examples of the content of the category.
Also from chapter/block level (3 notes)
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis