Alphabetic Index FY2027

D63.0

Anemia in neoplastic disease

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D60–D64 Aplastic and other anemias and other bone marrow failure syndromes

BillableComplete code, valid to report
Care settingsHospice: not accepted as primary

D63.0 (also written D630) is a billable ICD-10-CM diagnosis code for anemia in neoplastic disease. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 3 codes in category D63 (Anemia in chronic diseases classified elsewhere). The Alphabetic Index lists it under 1 entry. Its coding notes include a Code first instruction, 1 Excludes1 entry and 10 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

When only the anemia is treated, the malignancy is sequenced first for anemia in neoplastic disease. For anemia due to chemotherapy or immunotherapy, the anemia code is first.

Guidelines I.C.2.c.1; I.C.2.c.2Anemia with a malignancy or its treatmentRead the official text

Code first

If the underlying condition listed here is present and known, sequence it first.

This code
  • neoplasm (C00-D49)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • aplastic anemia due to antineoplastic chemotherapy (D61.1)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

This code
  • anemia due to antineoplastic chemotherapy (D64.81)
Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospice: not accepted as primary

Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Manifestation code. Report the underlying condition first (see the Code first note).

Source: CMS Integrated Outpatient Code Editor (IOCE) v27.3, effective October 1, 2026, edit 86

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry