Z15.81

Genetic susceptibility to multiple endocrine neoplasia [MEN]

FY2027Chapter 21: Factors influencing health status and contact with health services/Z14–Z15 Genetic carrier and genetic susceptibility to disease

BillableComplete code, valid to report

Z15.81 (also written Z1581) is a billable ICD-10-CM diagnosis code for genetic susceptibility to multiple endocrine neoplasia [MEN]. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 14 codes in category Z15 (Genetic susceptibility to disease). The Alphabetic Index lists it under 2 entries. Its coding notes include a Use additional code instruction and 2 Excludes1 entries.

Use additional code

Add the listed code as a secondary code, if known.

Inherited from Z15 Genetic susceptibility to disease
  • code, if applicable, for any associated family history of the disease (Z80-Z84)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • multiple endocrine neoplasia [MEN] syndromes (E31.2-)
Inherited from Z15 Genetic susceptibility to disease

Includes

Further defines or gives examples of the content of the category.

Inherited from Z15 Genetic susceptibility to disease
  • confirmed abnormal gene

Notes

Also from chapter/block level (3 notes)
Inherited from Chapter 21 Factors influencing health status and contact with health services
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries