Z15
Genetic susceptibility to disease
Z15 is a non-billable ICD-10-CM code category for genetic susceptibility to disease. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are Z15.0 Genetic susceptibility to malignant neoplasm, Z15.1 Genetic susceptibility to epilepsy and neurodevelopmental disorders, Z15.2 Genetic susceptibility to obesity, Z15.3 Genetic susceptibility to kidney disease and 1 more. Its coding notes include a Use additional code instruction and 1 Excludes1 entry.
Use additional code
Add the listed code as a secondary code, if known.
- code, if applicable, for any associated family history of the disease (Z80-Z84)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- chromosomal anomalies (Q90-Q99)
Includes
Further defines or gives examples of the content of the category.
- confirmed abnormal gene
Notes
Also from chapter/block level (3 notes)
- Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
- (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
- (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.