D72.0
Genetic anomalies of leukocytes
D72.0 (also written D720) is a billable ICD-10-CM diagnosis code for genetic anomalies of leukocytes. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 22 codes in category D72 (Other disorders of white blood cells). The Alphabetic Index lists it under 26 entries. Its coding notes include 4 Excludes1 entries and 10 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Alder (granulation) (granulocyte) anomaly
- Alder syndrome
- Hereditary leukocytic hypersegmentation
- Hereditary leukocytic hyposegmentation
- Hereditary leukomelanopathy
- May-Hegglin (granulation) (granulocyte) anomaly
- May-Hegglin syndrome
- Pelger-Huët (granulation) (granulocyte) anomaly
- Pelger-Huët syndrome
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 26 entries
- Alder (-Reilly) anomaly or syndrome (leukocyte granulation)
- Anomaly, anomalous (congenital) (unspecified type), Alder (-Reilly) (leukocyte granulation)
- Anomaly, anomalous (congenital) (unspecified type), granulation or granulocyte, genetic (constitutional) (leukocyte)
- Anomaly, anomalous (congenital) (unspecified type), Hegglin's
- Anomaly, anomalous (congenital) (unspecified type), hypersegmentation of neutrophils, hereditary
- Anomaly, anomalous (congenital) (unspecified type), Jordan's
- Anomaly, anomalous (congenital) (unspecified type), leukocytes, genetic
- Anomaly, anomalous (congenital) (unspecified type), leukocytes, genetic, granulation (constitutional)
- Anomaly, anomalous (congenital) (unspecified type), May (-Hegglin)
- Anomaly, anomalous (congenital) (unspecified type), Pelger-Huët (hereditary hyposegmentation)
- Dohle body panmyelopathic syndrome
- Dysgenesis, reticular
Show 14 more
- Hegglin's anomaly or syndrome
- Hypersegmentation, leukocytic, hereditary
- Hyposegmentation, leukocytic, hereditary
- Inclusion, azurophilic leukocytic
- Jordan's anomaly or syndrome
- Leukomelanopathy, hereditary
- May (-Hegglin) anomaly or syndrome
- Neutrophilia, hereditary giant
- Pelger-Huët anomaly or syndrome
- Syndrome, Alder's
- Syndrome, Döhle body-panmyelopathic
- Syndrome, Hegglin's
- Syndrome, May (-Hegglin)
- Syndrome, Pelger-Huet