D76

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D70–D77 Other disorders of blood and blood-forming organs

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

D76 is a non-billable ICD-10-CM code category for other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D76.1 Hemophagocytic lymphohistiocytosis; D76.2 Hemophagocytic syndrome, infection-associated and D76.3 Other histiocytosis syndromes. Its coding notes include 15 Excludes1 entries and 9 Excludes2 entries.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • (Abt-) Letterer-Siwe disease (C96.0)
  • eosinophilic granuloma (C96.6)
  • Hand-Schüller-Christian disease (C96.5)
  • histiocytic medullary reticulosis (C96.9)
  • histiocytic sarcoma (C96.A)
  • histiocytosis X, multifocal (C96.5)
  • histiocytosis X, unifocal (C96.6)
  • Langerhans-cell histiocytosis, multifocal (C96.5)
  • Langerhans-cell histiocytosis NOS (C96.6)
  • Langerhans-cell histiocytosis, unifocal (C96.6)
  • leukemic reticuloendotheliosis (C91.4-)
  • lipomelanotic reticulosis (I89.8)
  • malignant histiocytosis (C96.A)
  • malignant reticulosis (C86.0)
  • nonlipid reticuloendotheliosis (C96.0)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes under D76 3