D64.4

Congenital dyserythropoietic anemia

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D60–D64 Aplastic and other anemias and other bone marrow failure syndromes

BillableComplete code, valid to report

D64.4 (also written D644) is a billable ICD-10-CM diagnosis code for congenital dyserythropoietic anemia. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 8 codes in category D64 (Other anemias). The Alphabetic Index lists it under 3 entries. Its coding notes include 4 Excludes1 entries and 9 Excludes2 entries.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • Blackfan-Diamond syndrome (D61.01)
  • Di Guglielmo's disease (C94.0)
Inherited from D64 Other anemias
  • refractory anemia (D46.-)
  • refractory anemia with excess blasts in transformation [RAEB T] (C92.0-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Inclusion terms

Conditions classified to this code.

This code
  • Dyshematopoietic anemia (congenital)

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 3 entries