Alphabetic Index FY2027

D52.1

Drug-induced folate deficiency anemia

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D50–D53 Nutritional anemias

BillableComplete code, valid to report
Care settingsHome Health Primary · MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases

D52.1 (also written D521) is a billable ICD-10-CM diagnosis code for drug-induced folate deficiency anemia. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 4 codes in category D52 (Folate deficiency anemia). The Alphabetic Index lists it under 3 entries. Its coding notes include a Use additional code instruction, 1 Excludes1 entry and 9 Excludes2 entries.

Use additional code

Add the listed code as a secondary code, if known.

This code
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from D52 Folate deficiency anemia
  • folate deficiency without anemia (E53.8)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 3 entries