E53.8
Deficiency of other specified B group vitamins
E53.8 (also written E538) is a billable ICD-10-CM diagnosis code for deficiency of other specified B group vitamins. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 4 codes in category E53 (Deficiency of other B group vitamins). The Alphabetic Index lists it under 30 entries. Its coding notes include 3 Excludes1 entries and 2 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- folate deficiency anemia (D52.-)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- vitamin B12 deficiency anemia (D51.-)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Biotin deficiency
- Cyanocobalamin deficiency
- Folate deficiency
- Folic acid deficiency
- Pantothenic acid deficiency
- Vitamin B12 deficiency
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 30 entries
- Acid, deficiency, folic
- Acid, deficiency, pantothenic
- Avitaminosis (multiple), B12
- Chacaleh
- Deficiency, deficient, biotin
- Deficiency, deficient, choline
- Deficiency, deficient, cyanocobalamin
- Deficiency, deficient, folate
- Deficiency, deficient, folic acid
- Deficiency, deficient, inositol (B complex)
- Deficiency, deficient, pantothenic acid
- Deficiency, deficient, vitamin (multiple) NOS, B12
Show 18 more
- Deficiency, deficient, vitamin (multiple) NOS, folic acid
- Deficiency, deficient, vitamin (multiple) NOS, group B, specified NEC
- Deficiency, deficient, vitamin (multiple) NOS, H (biotin)
- Degeneration, degenerative, brain (cortical) (progressive), in, vitamin B12 deficiency
- Degeneration, degenerative, combined (spinal cord) (subacute)
- Degeneration, degenerative, combined (spinal cord) (subacute), in (due to), vitamin B12 deficiency
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), vitamin B12 deficiency
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), vitamin B12 deficiency, with behavioral disturbance
- Electric feet syndrome
- Lightning (effects) (stroke) (struck by), foot
- Melalgia, nutritional
- Myelopathy (spinal cord), vitamin B12
- Neuropathy, neuropathic, vitamin B12
- Painful, feet syndrome
- Polyneuropathy (peripheral), in (due to), vitamin B12 deficiency
- Syndrome, electric feet
- Syndrome, Gopalan's (burning feet)
- Syndrome, painful, feet