E52
Niacin deficiency [pellagra]
E52 is a billable ICD-10-CM diagnosis code for niacin deficiency [pellagra]. It is part of the FY2027 code set, effective October 1, 2026. The Alphabetic Index lists it under 28 entries. Its coding notes include 2 Excludes1 entries and 1 Excludes2 entry.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- sequelae of niacin deficiency (E64.8)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Niacin (-tryptophan) deficiency
- Nicotinamide deficiency
- Pellagra (alcoholic)
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 28 entries
- Acid, deficiency, amide nicotinic
- Acid, deficiency, nicotinic
- Alcohol, alcoholic, alcohol-induced, pellagra
- Avitaminosis (multiple), B, with, pellagra
- Avitaminosis (multiple), nicotinic acid
- Cheilosis (angular), with pellagra
- Deficiency, deficient, niacin (amide) (-tryptophan)
- Deficiency, deficient, nicotinamide
- Deficiency, deficient, nicotinic acid
- Deficiency, deficient, vitamin (multiple) NOS, B (complex) NOS, with, pellagra
- Deficiency, deficient, vitamin (multiple) NOS, nicotinic
- Deficiency, deficient, vitamin (multiple) NOS, PP (pellagra-preventing)
Show 16 more
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), niacin deficiency
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), niacin deficiency, with behavioral disturbance
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), pellagra
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), pellagra, with behavioral disturbance
- Dermatitis (eczematous), pellagrous
- Encephalopathy (acute), pellagrous
- Erythema, erythematous (infectional) (inflammation), endemic
- Gingivitis, pellagrous
- Glossitis (chronic superficial) (gangrenous) (Moeller's), pellagrous
- Niacin (amide) deficiency
- Nicotinic acid deficiency
- Pellagra (alcoholic)
- Pellagra (alcoholic), with, polyneuropathy
- Polioencephalopathy, superior hemorrhagic, with, pellagra
- Polyneuropathy (peripheral), in (due to), pellagra
- Syndrome, pellagroid