Alphabetic Index FY2027

T80.82XD

Complication of immune effector cellular therapy, subsequent encounter

FY2027Chapter 19: Injury, poisoning and certain other consequences of external causes/T80–T88 Complications of surgical and medical care, not elsewhere classified

BillableComplete code, valid to report
Care settingsHome Health Primary · MMTA - Other

T80.82XD (also written T8082XD) is a billable ICD-10-CM diagnosis code for complication of immune effector cellular therapy, subsequent encounter. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 114 codes in category T80 (Complications following infusion, transfusion and therapeutic injection). The Alphabetic Index lists it under 3 entries. Its 7th character, D, means subsequent encounter. Its coding notes include a Use additional code instruction and 33 Excludes2 entries.

7th character

Category T80 requires a 7th character. T80.82 has only 5 characters, so a placeholder X fills the 6th position.

Assembled code T80.82XD Open code

Guidelines tips

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

The 7th character depends on whether the patient is in active treatment, not on who sees the patient. An aftercare Z code is not used for injury aftercare.

Guidelines I.C.19.aInjuries: application of 7th charactersRead the official text

A complication code needs the provider's documented cause-and-effect link between the care and the condition. Some T codes already include the type of procedure, so no external cause code is needed.

Guidelines I.B.16; I.C.19.g.4Complications of careRead the official text

Use additional code

Add the listed code as a secondary code, if known.

Inherited from T80.82 Complication of immune effector cellular therapy
  • code to identify the specific complication, such as:
    • cytokine release syndrome (D89.83-)
    • immune effector cell-associated neurotoxicity syndrome (G92.0-)
Also from chapter/block level (4 notes)
Inherited from T80–T88 Complications of surgical and medical care, not elsewhere classified
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code(s) to identify the specified condition resulting from the complication
  • code to identify devices involved and details of circumstances (Y62-Y82)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • code to identify any retained foreign body, if applicable (Z18.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from T80.82 Complication of immune effector cellular therapy
  • adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
  • complication of bone marrow transplant (T86.0)
  • complication of stem cell transplant (T86.5)
Inherited from T80 Complications following infusion, transfusion and therapeutic injection
  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)
Also from chapter/block level (23 notes)
Inherited from T80–T88 Complications of surgical and medical care, not elsewhere classified
  • any encounters with medical care for postprocedural conditions in which no complications are present, such as:
    • artificial opening status (Z93.-)
    • closure of external stoma (Z43.-)
    • fitting and adjustment of external prosthetic device (Z44.-)
    • burns and corrosions from local applications and irradiation (T20-T32)
    • complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
    • mechanical complication of respirator [ventilator] (J95.850)
    • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
    • postprocedural fever (R50.82)
  • specified complications classified elsewhere, such as:
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Includes

Further defines or gives examples of the content of the category.

Inherited from T80 Complications following infusion, transfusion and therapeutic injection
  • complications following perfusion

Inclusion terms

Conditions classified to this code.

Inherited from T80.82 Complication of immune effector cellular therapy
  • Complication of chimeric antigen receptor (CAR-T) cell therapy
  • Complication of IEC therapy

Notes

Also from chapter/block level (2 notes)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

Alphabetic Index terms

Terms the official Alphabetic Index lists for T80.82. This code adds the 7th character. 3 entries