Alphabetic Index FY2027

L49.3

Exfoliation due to erythematous condition involving 30-39 percent of body surface

FY2027Chapter 12: Diseases of the skin and subcutaneous tissue/L49–L54 Urticaria and erythema

BillableComplete code, valid to report
Care settingsHospice: not accepted as primaryHospital CC

L49.3 (also written L493) is a billable ICD-10-CM diagnosis code for exfoliation due to erythematous condition involving 30-39 percent of body surface. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 10 codes in category L49 (Exfoliation due to erythematous conditions according to extent of body surface involved). The Alphabetic Index lists it under 1 entry. Its coding notes include a Code first instruction, 2 Excludes1 entries and 10 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

Inherited from L49 Exfoliation due to erythematous conditions according to extent of body surface involved
  • erythematous condition causing exfoliation, such as:
    • Ritter's disease (L00)
    • (Staphylococcal) scalded skin syndrome (L00)
    • Stevens-Johnson syndrome (L51.1)
    • Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome (L51.3)
    • Toxic epidermal necrolysis (L51.2)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Also from chapter/block level (2 notes)
Inherited from L49–L54 Urticaria and erythema

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 12 Diseases of the skin and subcutaneous tissue
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • lipomelanotic reticulosis (I89.8)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • viral warts (B07.-)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospice: not accepted as primary

Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Supplementary or additional code, not allowed as principal diagnosis.

Source: CMS Integrated Outpatient Code Editor (IOCE) v27.3, effective October 1, 2026, edit 113

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. No principal diagnosis cancels it. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry