L51.3

Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome

FY2027Chapter 12: Diseases of the skin and subcutaneous tissue/L49–L54 Urticaria and erythema

BillableComplete code, valid to report

L51.3 (also written L513) is a billable ICD-10-CM diagnosis code for stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 6 codes in category L51 (Erythema multiforme). The Alphabetic Index lists it under 2 entries. Its coding notes include a Use additional code instruction, 4 Excludes1 entries and 10 Excludes2 entries.

Use additional code

Add the listed code as a secondary code, if known.

Inherited from L51 Erythema multiforme
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code to identify associated manifestations, such as:
    • arthropathy associated with dermatological disorders (M14.8-)
    • conjunctival edema (H11.42)
    • conjunctivitis (H10.22-)
    • corneal scars and opacities (H17.-)
    • corneal ulcer (H16.0-)
    • edema of eyelid (H02.84-)
    • inflammation of eyelid (H01.8-)
    • keratoconjunctivitis sicca (H16.22-)
    • mechanical lagophthalmos (H02.22-)
    • stomatitis (K12.-)
    • symblepharon (H11.23-)
    • code to identify percentage of skin exfoliation (L49.-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from L51 Erythema multiforme
  • staphylococcal scalded skin syndrome (L00)
  • Ritter's disease (L00)
Also from chapter/block level (2 notes)
Inherited from L49–L54 Urticaria and erythema

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 12 Diseases of the skin and subcutaneous tissue
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • lipomelanotic reticulosis (I89.8)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • viral warts (B07.-)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 35 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Inclusion terms

Conditions classified to this code.

This code
  • SJS-TEN overlap syndrome

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries