K76.81

Hepatopulmonary syndrome

FY2027Chapter 11: Diseases of the digestive system/K70–K77 Diseases of liver

BillableComplete code, valid to report

K76.81 (also written K7681) is a billable ICD-10-CM diagnosis code for hepatopulmonary syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 13 codes in category K76 (Other diseases of liver). The Alphabetic Index lists it under 1 entry. Its coding notes include a Code first instruction, 1 Excludes1 entry and 20 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

This code
  • underlying liver disease, such as:
    • alcoholic cirrhosis of liver (K70.3-)
    • cirrhosis of liver without mention of alcohol (K74.6-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Also from chapter/block level (1 note)
Inherited from K70–K77 Diseases of liver
  • jaundice NOS (R17)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from K76 Other diseases of liver
  • alcoholic liver disease (K70.-)
  • amyloid degeneration of liver (E85.-)
  • cystic disease of liver (congenital) (Q44.6)
  • hepatic vein thrombosis (I82.0)
  • hepatomegaly NOS (R16.0)
  • pigmentary cirrhosis (of liver) (E83.110)
  • portal vein thrombosis (I81)
  • toxic liver disease (K71.-)
Also from chapter/block level (12 notes)
Inherited from K70–K77 Diseases of liver
Inherited from Chapter 11 Diseases of the digestive system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Gastrointestinal tract and Genitourinary system clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry