K72.01

Acute and subacute hepatic failure with coma

FY2027Chapter 11: Diseases of the digestive system/K70–K77 Diseases of liver

BillableComplete code, valid to report

K72.01 (also written K7201) is a billable ICD-10-CM diagnosis code for acute and subacute hepatic failure with coma. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 6 codes in category K72 (Hepatic failure, not elsewhere classified). The Alphabetic Index lists it under 4 entries. Its coding notes include a Use additional code instruction, 5 Excludes1 entries and 15 Excludes2 entries.

Use additional code

Add the listed code as a secondary code, if known.

Inherited from K72 Hepatic failure, not elsewhere classified
  • code, if applicable, for ascites (R18.8)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from K72 Hepatic failure, not elsewhere classified
  • alcoholic hepatic failure (K70.4)
  • hepatic failure with toxic liver disease (K71.1-)
  • icterus of newborn (P55-P59)
  • postprocedural hepatic failure (K91.82)
Also from chapter/block level (1 note)
Inherited from K70–K77 Diseases of liver
  • jaundice NOS (R17)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from K72 Hepatic failure, not elsewhere classified
  • hepatic failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8)
  • hepatic failure complicating pregnancy, childbirth and the puerperium (O26.6-)
  • viral hepatitis with hepatic coma (B15-B19)
Also from chapter/block level (12 notes)
Inherited from K70–K77 Diseases of liver
Inherited from Chapter 11 Diseases of the digestive system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Gastrointestinal tract and Genitourinary system clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital MCC

Counts as a major complication or comorbidity (MCC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 8 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Includes

Further defines or gives examples of the content of the category.

Inherited from K72 Hepatic failure, not elsewhere classified
  • fulminant hepatitis NEC, with hepatic failure
  • liver (cell) necrosis with hepatic failure
  • malignant hepatitis NEC, with hepatic failure
  • yellow liver atrophy or dystrophy

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 4 entries