J45.22

Mild intermittent asthma with status asthmaticus

FY2027Chapter 10: Diseases of the respiratory system/J40–J4B Chronic lower respiratory diseases

BillableComplete code, valid to report

J45.22 (also written J4522) is a billable ICD-10-CM diagnosis code for mild intermittent asthma with status asthmaticus. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 18 codes in category J45 (Asthma). The Alphabetic Index lists it under 2 entries. Its coding notes include a Use additional code instruction, 5 Excludes1 entries and 14 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

An exacerbation is a worsening of the chronic condition. An infection alone does not make it one.

Guidelines I.C.10.a.1COPD and asthma: acute exacerbationRead the official text

Use additional code

Add the listed code as a secondary code, if known.

Inherited from J45 Asthma
  • code to identify:
    • eosinophilic asthma (J82.83)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
Also from chapter/block level (7 notes)
Inherited from Chapter 10 Diseases of the respiratory system
  • code, where applicable, to identify:
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from J45 Asthma
Also from chapter/block level (1 note)
Inherited from J40–J4B Chronic lower respiratory diseases
  • bronchitis due to chemicals, gases, fumes and vapors (J68.0)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from J45 Asthma
  • asthma with chronic obstructive pulmonary disease (J44.89)
  • chronic asthmatic (obstructive) bronchitis (J44.89)
  • chronic obstructive asthma (J44.89)
  • other specified chronic obstructive pulmonary disease (J44.89)
Also from chapter/block level (10 notes)
Inherited from J40–J4B Chronic lower respiratory diseases
Inherited from Chapter 10 Diseases of the respiratory system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • smoke inhalation (T59.81-)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Respiratory clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 29 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Includes

Further defines or gives examples of the content of the category.

Inherited from J45 Asthma
  • allergic (predominantly) asthma
  • allergic bronchitis NOS
  • allergic rhinitis with asthma
  • atopic asthma
  • extrinsic allergic asthma
  • hay fever with asthma
  • idiosyncratic asthma
  • intrinsic nonallergic asthma
  • nonallergic asthma

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 10 Diseases of the respiratory system
  • When a respiratory condition is described as occurring in more than one site and is not specifically indexed, it should be classified to the lower anatomic site (e.g. tracheobronchitis to bronchitis in J40).

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries