J45.5
Severe persistent asthma
J45.5 is a non-billable ICD-10-CM code header for severe persistent asthma. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are J45.50 Severe persistent asthma, uncomplicated; J45.51 Severe persistent asthma with (acute) exacerbation and J45.52 Severe persistent asthma with status asthmaticus. Its coding notes include a Use additional code instruction, 5 Excludes1 entries and 14 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
An exacerbation is a worsening of the chronic condition. An infection alone does not make it one.
Use additional code
Add the listed code as a secondary code, if known.
Also from chapter/block level (7 notes)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (10 notes)
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- smoke inhalation (T59.81-)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Includes
Further defines or gives examples of the content of the category.
- allergic (predominantly) asthma
- allergic bronchitis NOS
- allergic rhinitis with asthma
- atopic asthma
- extrinsic allergic asthma
- hay fever with asthma
- idiosyncratic asthma
- intrinsic nonallergic asthma
- nonallergic asthma
Notes
Also from chapter/block level (1 note)
- When a respiratory condition is described as occurring in more than one site and is not specifically indexed, it should be classified to the lower anatomic site (e.g. tracheobronchitis to bronchitis in J40).