E25.8
Other adrenogenital disorders
E25.8 (also written E258) is a billable ICD-10-CM diagnosis code for other adrenogenital disorders. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 3 codes in category E25 (Adrenogenital disorders). The Alphabetic Index lists it under 11 entries. Its coding notes include a Use additional code instruction and 5 Excludes1 entries.
Use additional code
Add the listed code as a secondary code, if known.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Endocrine clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Includes
Further defines or gives examples of the content of the category.
- adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
- Female adrenal pseudohermaphroditism
- Female heterosexual precocious pseudopuberty
- Male isosexual precocious pseudopuberty
- Male macrogenitosomia praecox
- Male sexual precocity with adrenal hyperplasia
- Male virilization (female)
Inclusion terms
Conditions classified to this code.
- Idiopathic adrenogenital disorder
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 11 entries
- Adrenogenital syndrome, acquired
- Disorder (of), adrenogenital, drug-induced
- Disorder (of), adrenogenital, iatrogenic
- Disorder (of), adrenogenital, idiopathic
- Pseudohermaphroditism, adrenal
- Pseudohermaphroditism, female, with adrenocortical disorder
- Pseudohermaphroditism, male, adrenal
- Pseudohermaphroditism, male, with, adrenocortical disorder
- Pseudopuberty, precocious, female heterosexual
- Pseudopuberty, precocious, male isosexual
- Puberty (development state), premature, due to, adrenal cortical hyperfunction