E24.2

Drug-induced Cushing's syndrome

FY2027Chapter 4: Endocrine, nutritional and metabolic diseases/E20–E35 Disorders of other endocrine glands

BillableComplete code, valid to report

E24.2 (also written E242) is a billable ICD-10-CM diagnosis code for drug-induced Cushing's syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 7 codes in category E24 (Cushing's syndrome). The Alphabetic Index lists it under 9 entries. Its coding notes include a Use additional code instruction and 4 Excludes1 entries.

Use additional code

Add the listed code as a secondary code, if known.

This code
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from E24 Cushing's syndrome
  • congenital adrenal hyperplasia (E25.0)
Also from chapter/block level (3 notes)
Inherited from E20–E35 Disorders of other endocrine glands
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Endocrine clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 23 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 9 entries