E16.3

Increased secretion of glucagon

FY2027Chapter 4: Endocrine, nutritional and metabolic diseases/E15–E16 Other disorders of glucose regulation and pancreatic internal secretion

BillableComplete code, valid to report

E16.3 (also written E163) is a billable ICD-10-CM diagnosis code for increased secretion of glucagon. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 10 codes in category E16 (Other disorders of pancreatic internal secretion). The Alphabetic Index lists it under 6 entries. Its coding notes include 1 Excludes1 entry.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Also from chapter/block level (1 note)
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

Inclusion terms

Conditions classified to this code.

This code
  • Hyperplasia of pancreatic endocrine cells with glucagon excess

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 6 entries