E15
Nondiabetic hypoglycemic coma
E15 is a billable ICD-10-CM diagnosis code for nondiabetic hypoglycemic coma. It is part of the FY2027 code set, effective October 1, 2026. The Alphabetic Index lists it under 8 entries. Its coding notes include 1 Excludes1 entry.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 355 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CHAC
On the CMS list of hospital-acquired conditions (HAC 09: Manifestations of Poor Glycemic Control). When the claim reports it with a present-on-admission (POA) indicator of N (not present) or U (documentation insufficient), CMS does not pay the CC or MCC DRG for it. A POA of Y (present) or W (clinically undetermined) is paid normally.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix I; CMS Hospital-Acquired Conditions (HAC) Coding page, POA indicator payment tableIncludes
Further defines or gives examples of the content of the category.
- drug-induced insulin coma in nondiabetic
- hyperinsulinism with hypoglycemic coma
- hypoglycemic coma NOS
Notes
Also from chapter/block level (1 note)
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 8 entries
- Coma, hypoglycemic (diabetic), nondiabetic
- Hyperinsulinism (functional), with, coma (hypoglycemic)
- Hypoglycemia (spontaneous), coma
- Hypoglycemia (spontaneous), drug-induced, with coma (nondiabetic)
- Hypoglycemia (spontaneous), due to insulin, with coma (nondiabetic)
- Hypoglycemia (spontaneous), iatrogenic, with coma (nondiabetic)
- Reaction, hypoglycemic, due to insulin, with coma (diabetic), nondiabetic
- Shock, insulin