Alphabetic Index FY2027

D69.42

Congenital and hereditary thrombocytopenia purpura

FY2027Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism/D65–D69 Coagulation defects, purpura and other hemorrhagic conditions

BillableComplete code, valid to report
Care settingsHospital CC

D69.42 (also written D6942) is a billable ICD-10-CM diagnosis code for congenital and hereditary thrombocytopenia purpura. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 13 codes in category D69 (Purpura and other hemorrhagic conditions). The Alphabetic Index lists it under 4 entries. Its coding notes include a Code first instruction, 9 Excludes1 entries and 9 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

This code
  • congential or hereditary disorder, such as:
    • thrombocytopenia with absent radius (TAR syndrome) (Q87.2)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from D69.4 Other primary thrombocytopenia
  • transient neonatal thrombocytopenia (P61.0)
  • Wiskott-Aldrich syndrome (D82.0)
Inherited from D69 Purpura and other hemorrhagic conditions
  • benign hypergammaglobulinemic purpura (D89.0)
  • cryoglobulinemic purpura (D89.1)
  • essential (hemorrhagic) thrombocythemia (D47.3)
  • hemorrhagic thrombocythemia (D47.3)
  • purpura fulminans (D65)
  • thrombotic thrombocytopenic purpura (M31.19)
  • Waldenström hypergammaglobulinemic purpura (D89.0)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 53 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Inclusion terms

Conditions classified to this code.

This code
  • Congenital thrombocytopenia
  • Hereditary thrombocytopenia

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 4 entries