D55.29
Anemia due to other disorders of glycolytic enzymes
D55.29 (also written D5529) is a billable ICD-10-CM diagnosis code for anemia due to other disorders of glycolytic enzymes. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 7 codes in category D55 (Anemia due to enzyme disorders). The Alphabetic Index lists it under 13 entries. Its coding notes include 2 Excludes1 entries and 9 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Hexokinase deficiency anemia
- Triose-phosphate isomerase deficiency anemia
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 13 entries
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, 2, 3 diphosphoglycurate mutase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, 2, 3 PG
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, enzyme, glycolytic
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, glyceraldehyde phosphate dehydrogenase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, hexokinase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, phosphofructo-aldolase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, phosphoglycerate kinase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, triose-phosphate isomerase
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hemolytic, nonspherocytic, congenital or hereditary NEC, type, II
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hemolytic, nonspherocytic, type, II
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hexokinase deficiency
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), with (due to) (in), disorder of, anaerobic glycolysis