D51.0
Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D51.0 (also written D510) is a billable ICD-10-CM diagnosis code for vitamin B12 deficiency anemia due to intrinsic factor deficiency. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 6 codes in category D51 (Vitamin B12 deficiency anemia). The Alphabetic Index lists it under 35 entries. Its coding notes include 10 Excludes2 entries.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (9 notes)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Inclusion terms
Conditions classified to this code.
- Addison anemia
- Biermer anemia
- Pernicious (congenital) anemia
- Congenital intrinsic factor deficiency
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 35 entries
- Addison's, anemia (pernicious)
- Addison-Biermer anemia (pernicious)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), Addison (-Biermer) (pernicious)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), Biermer's (pernicious)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), combined system disease NEC
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), congenital, pernicious
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), cytogenic
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, vitamin B12 NOS, due to, intrinsic factor deficiency
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), deficiency, vitamin B12 NOS, pernicious
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), malignant (progressive)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), pernicious (congenital) (malignant) (progressive)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), progressive, malignant
Show 23 more
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), progressive, pernicious
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), vitamin, B12 deficiency (dietary) pernicious
- Biermer's (pernicious) anemia or disease
- Congenital, intrinsic factor deficiency
- Deficiency, deficient, intrinsic, factor (congenital)
- Degeneration, degenerative, combined (spinal cord) (subacute), with anemia (pernicious)
- Disease, diseased, Addison's anemia (pernicious)
- Disease, diseased, Biermer's (pernicious anemia)
- Disease, diseased, Lichtheim's (subacute combined sclerosis with pernicious anemia)
- Disease, diseased, Putnam's (subacute combined sclerosis with pernicious anemia)
- Disease, diseased, Runeberg's (progressive pernicious anemia)
- Glossitis (chronic superficial) (gangrenous) (Moeller's), Hunter's
- Hunter's, glossitis
- Lichtheim's disease or syndrome
- Myasthenia, syndrome, in, pernicious anemia
- Myelopathy (spinal cord), in (due to), pernicious anemia
- Neuropathy, neuropathic, vitamin B12, with anemia (pernicious)
- Polyneuropathy (peripheral), in (due to), vitamin B12 deficiency, with anemia (pernicious)
- Runeberg's disease
- Syndrome, Dana-Putnam
- Syndrome, hunterian glossitis
- Syndrome, Lichtheim's
- Syndrome, Putnam-Dana