Z80.49

Family history of malignant neoplasm of other genital organs

FY2027Chapter 21: Factors influencing health status and contact with health services/Z77–Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status

BillableComplete code, valid to report

Z80.49 (also written Z8049) is a billable ICD-10-CM diagnosis code for family history of malignant neoplasm of other genital organs. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 16 codes in category Z80 (Family history of primary malignant neoplasm). The Alphabetic Index lists it under 2 entries. Its coding notes include a Code also instruction.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

History codes can go on any record. The reason for the encounter is sequenced first, with history codes as additional diagnoses.

Guidelines I.C.21.c.4Personal and family history Z codesRead the official text

Code also

Two codes may be needed to describe the condition. This note gives no sequencing order.

Also from chapter/block level (1 note)
Inherited from Z77–Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
  • any follow-up examination (Z08-Z09)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospice: not accepted as primary

Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Supplementary or additional code, not allowed as principal diagnosis.

Source: CMS Integrated Outpatient Code Editor (IOCE) v27.3, effective October 1, 2026, edit 113

Notes

Also from chapter/block level (3 notes)
Inherited from Chapter 21 Factors influencing health status and contact with health services
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries