Z29.81

Encounter for HIV pre-exposure prophylaxis

FY2027Chapter 21: Factors influencing health status and contact with health services/Z20–Z29 Persons with potential health hazards related to communicable diseases

BillableComplete code, valid to report

Z29.81 (also written Z2981) is a billable ICD-10-CM diagnosis code for encounter for HIV pre-exposure prophylaxis. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 8 codes in category Z29 (Encounter for other prophylactic measures). The Alphabetic Index lists it under 3 entries. Its coding notes include a Code also instruction and 2 Excludes1 entries.

Code also

Two codes may be needed to describe the condition. This note gives no sequencing order.

This code
  • , if applicable, risk factors for HIV, such as:
    • contact with and (suspected) exposure to human immunodeficiency virus [HIV] (Z20.6)
    • high risk sexual behavior (Z72.5-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from Z29 Encounter for other prophylactic measures
  • desensitization to allergens (Z51.6)
  • prophylactic surgery (Z40.-)

Notes

Also from chapter/block level (3 notes)
Inherited from Chapter 21 Factors influencing health status and contact with health services
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 3 entries