Z21

Asymptomatic human immunodeficiency virus [HIV] infection status

FY2027Chapter 21: Factors influencing health status and contact with health services/Z20–Z29 Persons with potential health hazards related to communicable diseases

BillableComplete code, valid to report

Z21 is a billable ICD-10-CM diagnosis code for asymptomatic human immunodeficiency virus [HIV] infection status. It is part of the FY2027 code set, effective October 1, 2026. The Alphabetic Index lists it under 7 entries. Its coding notes include a Code first instruction and 5 Excludes1 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

This code
  • Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • acquired immunodeficiency syndrome (B20)
  • contact with human immunodeficiency virus [HIV] (Z20.6)
  • exposure to human immunodeficiency virus [HIV] (Z20.6)
  • human immunodeficiency virus [HIV] disease (B20)
  • inconclusive laboratory evidence of human immunodeficiency virus [HIV] (R75)

Inclusion terms

Conditions classified to this code.

This code
  • HIV positive NOS

Notes

Also from chapter/block level (3 notes)
Inherited from Chapter 21 Factors influencing health status and contact with health services
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 7 entries