T43.611A

Poisoning by caffeine, accidental (unintentional), initial encounter

FY2027Chapter 19: Injury, poisoning and certain other consequences of external causes/T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances

T43.611A (also written T43611A) is a billable ICD-10-CM diagnosis code for poisoning by caffeine, accidental (unintentional), initial encounter. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 354 codes in category T43 (Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified). Its 7th character, A, means initial encounter. Its coding notes include a Code first instruction, a Use additional code instruction, 2 Excludes1 entries and 13 Excludes2 entries.

7th character

Category T43 requires a 7th character.

Assembled code T43.611A Open code

Guidelines tips

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

The 7th character depends on whether the patient is in active treatment, not on who sees the patient. An aftercare Z code is not used for injury aftercare.

Guidelines I.C.19.aInjuries: application of 7th charactersRead the official text

T36-T65 codes already include the substance and the intent, so no additional external cause code is required. Do not code directly from the Table of Drugs and Chemicals.

Guidelines I.C.19.ePoisoning, adverse effects and the Table of DrugsRead the official text

Code first

If the underlying condition listed here is present and known, sequence it first.

Also from chapter/block level (7 notes)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • , for adverse effects, the nature of the adverse effect, such as:
    • adverse effect NOS (T88.7)
    • aspirin gastritis (K29.-)
    • blood disorders (D56-D76)
    • contact dermatitis (L23-L25)
    • dermatitis due to substances taken internally (L27.-)
    • nephropathy (N14.0-N14.2)

Use additional code

Add the listed code as a secondary code, if known.

Also from chapter/block level (5 notes)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • code(s) to specify:
    • manifestations of poisoning
    • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
    • underdosing of medication regimen (Z91.12-, Z91.13-)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • code to identify any retained foreign body, if applicable (Z18.-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from T43.6 Poisoning by, adverse effect of and underdosing of psychostimulants
  • poisoning by, adverse effect of and underdosing of cocaine (T40.5-)
Also from chapter/block level (1 note)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
  • appetite depressants (T50.5-)
  • barbiturates (T42.3-)
  • benzodiazepines (T42.4-)
  • drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.- -F19.-)
  • methaqualone (T42.6-)
  • psychodysleptics [hallucinogens] (T40.7-T40.9-)
Also from chapter/block level (7 notes)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

IPF Primary

IPF MS-DRG adjustment. A principal diagnosis of this code groups to one of these MS-DRGs. Which one depends on other facts of the stay, so the factor is a range:

MS-DRGDescriptionFactor
917Poisoning and toxic effects of drugs w MCC1.19
918Poisoning and toxic effects of drugs w/out MCC1.12
A principal diagnosis that groups to none of the 19 designated MS-DRGs gets no MS-DRG adjustment. Otherwise the claim still receives the federal per diem base rate and the other adjustments.

Source: CMS IPF PPS FY 2027 final rule (CMS-1847-F), Addendum A; code lists from the CMS MS-DRG Definitions Manual v44; effective for discharges on or after October 1, 2026

IPF Comorbidity

On the CMS IPF comorbidity list.

Comorbidity categoryFactor
Poisoning1.16
It counts as a comorbidity when reported as a secondary diagnosis and actively treated during the stay. An IPF receives only one adjustment within a category and can receive adjustments in more than one category.

Source: CMS IPF PPS FY 2027 final rule (CMS-1847-F), Addendum B-3 (comorbidity codes with adjustment factor); effective for discharges on or after October 1, 2026

Includes

Further defines or gives examples of the content of the category.

Also from chapter/block level (4 notes)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Inclusion terms

Conditions classified to this code.

Inherited from T43.611 Poisoning by caffeine, accidental
  • Poisoning by caffeine NOS

Notes

Also from chapter/block level (3 notes)
Inherited from T36–T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.