Q78.0
Osteogenesis imperfecta
Q78.0 (also written Q780) is a billable ICD-10-CM diagnosis code for osteogenesis imperfecta. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 9 codes in category Q78 (Other osteochondrodysplasias). The Alphabetic Index lists it under 26 entries. Its coding notes include 2 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
Chapter 17 codes can be used for life. Manifestations that are an inherent part of a specifically coded anomaly are not coded separately. A corrected malformation is reported with a personal history code.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (1 note)
- inborn errors of metabolism (E70-E88)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the Musculoskeletal Rehabilitation clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026IRF 60% Rule
On the CMS list of diagnoses used to determine presumptive compliance with the IRF 60 percent rule.
Source: CMS IRF Presumptive Compliance-3, FY 2027 IRF PPS final rule files, effective for discharges on or after October 1, 2026Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 10 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CInclusion terms
Conditions classified to this code.
- Fragilitas ossium
- Osteopsathyrosis
Notes
Also from chapter/block level (1 note)
- Codes from this chapter are not for use on maternal records
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 26 entries
- Adair-Dighton syndrome (brittle bones and blue sclera, deafness)
- Blue, sclera, with fragility of bone and deafness
- Brittle, bones disease
- Deafness (acquired) (complete) (hereditary) (partial), congenital, with blue sclera and fragility of bone
- Deafness (acquired) (complete) (hereditary) (partial), with blue sclera and fragility of bone
- Disease, diseased, Eddowes' (brittle bones and blue sclera)
- Disease, diseased, Lobstein's (brittle bones and blue sclera)
- Disease, diseased, Vrolik's (osteogenesis imperfecta)
- Eddowes (-Spurway) syndrome
- Ekman's syndrome (brittle bones and blue sclera)
- Fragile, fragility, bone, congenital (with blue sclera)
- Fragilitas, ossium (with blue sclerae) (hereditary)
Show 14 more
- Lobstein (-Ekman) disease or syndrome
- Osteitis, fragilitans
- Osteogenesis imperfecta
- Osteopsathyrosis (idiopathica)
- Spurway's syndrome
- Syndrome, Adair-Dighton
- Syndrome, blue sclera
- Syndrome, Dighton's
- Syndrome, Eddowes'
- Syndrome, Ekman's
- Syndrome, Spurway's
- Syndrome, van der Hoeve's
- Van der Hoeve (-de Kleyn) syndrome
- Vrolik's disease