P55.1
ABO isoimmunization of newborn
P55.1 (also written P551) is a billable ICD-10-CM diagnosis code for ABO isoimmunization of newborn. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 4 codes in category P55 (Hemolytic disease of newborn). The Alphabetic Index lists it under 11 entries. Its coding notes include 5 Excludes1 entries and 5 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
Chapter 16 codes are never used on the maternal record, and chapter 15 codes are never used on the newborn record. Chapter 16 codes can be used for life if the condition persists.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (5 notes)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- tetanus neonatorum (A33)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Includes
Further defines or gives examples of the content of the category.
Also from chapter/block level (1 note)
- conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Notes
Also from chapter/block level (1 note)
- Codes from this chapter are for use on newborn records only, never on maternal records
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 11 entries
- Abocclusion, hemolytic disease (newborn)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), newborn, due to, ABO (antibodies, isoimmunization, maternal/fetal incompatibility)
- Disease, diseased, hemolytic (newborn), due to or with, incompatibility, ABO (blood group)
- Erythroblastosis (fetalis) (newborn), due to, ABO (antibodies) (incompatibility) (isoimmunization)
- Immunization, ABO, in newborn
- Incompatibility, ABO, newborn
- Isoimmunization NEC, newborn, ABO (blood groups)
- Jaundice (yellow), newborn, due to or associated with, ABO, antibodies
- Jaundice (yellow), newborn, due to or associated with, ABO, incompatibility, maternal/fetal
- Jaundice (yellow), newborn, due to or associated with, ABO, isoimmunization
- Jaundice (yellow), newborn, due to or associated with, hemolytic disease, ABO isoimmunization