Alphabetic Index FY2027

P04.49

Newborn affected by maternal use of other drugs of addiction

FY2027Chapter 16: Certain conditions originating in the perinatal period/P00–P04 Newborn affected by maternal factors and by complications of pregnancy, labor, and delivery

BillableComplete code, valid to report

P04.49 (also written P0449) is a billable ICD-10-CM diagnosis code for newborn affected by maternal use of other drugs of addiction. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 22 codes in category P04 (Newborn affected by noxious substances transmitted via placenta or breast milk). The Alphabetic Index lists it under 4 entries. Its coding notes include a Code first instruction and 11 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

Chapter 16 codes are never used on the maternal record, and chapter 15 codes are never used on the newborn record. Chapter 16 codes can be used for life if the condition persists.

Guidelines I.C.16.a.1Perinatal codes and the maternal recordRead the official text

Code first

If the underlying condition listed here is present and known, sequence it first.

Inherited from P04 Newborn affected by noxious substances transmitted via placenta or breast milk
  • any current condition in newborn, if applicable

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

This code
  • newborn affected by maternal anesthesia and analgesia (P04.0)
  • withdrawal symptoms from maternal use of drugs of addiction (P96.1)
Inherited from P04 Newborn affected by noxious substances transmitted via placenta or breast milk
  • congenital malformations (Q00-Q99)
  • encounter for observation of newborn for suspected diseases and conditions ruled out (Z05.-)
  • neonatal jaundice from excessive hemolysis due to drugs or toxins transmitted from mother (P58.4)
  • newborn in contact with and (suspected) exposures hazardous to health not transmitted via placenta or breast milk (Z77.-)
Also from chapter/block level (5 notes)
Inherited from Chapter 16 Certain conditions originating in the perinatal period
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Includes

Further defines or gives examples of the content of the category.

Inherited from P04 Newborn affected by noxious substances transmitted via placenta or breast milk
  • nonteratogenic effects of substances transmitted via placenta
Also from chapter/block level (1 note)
Inherited from Chapter 16 Certain conditions originating in the perinatal period
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Notes

Also from chapter/block level (2 notes)
Inherited from P00–P04 Newborn affected by maternal factors and by complications of pregnancy, labor, and delivery
  • These codes are for use when the listed maternal conditions are specified as the cause of confirmed morbidity or potential morbidity which have their origin in the perinatal period (before birth through the first 28 days after birth).
Inherited from Chapter 16 Certain conditions originating in the perinatal period
  • Codes from this chapter are for use on newborn records only, never on maternal records

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 4 entries