P04.12
Newborn affected by maternal cytotoxic drugs
P04.12 (also written P0412) is a billable ICD-10-CM diagnosis code for newborn affected by maternal cytotoxic drugs. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 22 codes in category P04 (Newborn affected by noxious substances transmitted via placenta or breast milk). The Alphabetic Index lists it under 1 entry. Its coding notes include a Code first instruction, 2 Excludes1 entries and 11 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
Chapter 16 codes are never used on the maternal record, and chapter 15 codes are never used on the newborn record. Chapter 16 codes can be used for life if the condition persists.
Code first
If the underlying condition listed here is present and known, sequence it first.
- any current condition in newborn, if applicable
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- congenital malformations (Q00-Q99)
- encounter for observation of newborn for suspected diseases and conditions ruled out (Z05.-)
- neonatal jaundice from excessive hemolysis due to drugs or toxins transmitted from mother (P58.4)
- newborn in contact with and (suspected) exposures hazardous to health not transmitted via placenta or breast milk (Z77.-)
Also from chapter/block level (5 notes)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- tetanus neonatorum (A33)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Includes
Further defines or gives examples of the content of the category.
- nonteratogenic effects of substances transmitted via placenta
Also from chapter/block level (1 note)
- conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Notes
Also from chapter/block level (2 notes)
- These codes are for use when the listed maternal conditions are specified as the cause of confirmed morbidity or potential morbidity which have their origin in the perinatal period (before birth through the first 28 days after birth).
- Codes from this chapter are for use on newborn records only, never on maternal records
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 1 entry