M87.159

Osteonecrosis due to drugs, unspecified femur

FY2027Chapter 13: Diseases of the musculoskeletal system and connective tissue/M86–M90 Other osteopathies

BillableComplete code, valid to report
Care settingsHospital CC

M87.159 (also written M87159) is a billable ICD-10-CM diagnosis code for osteonecrosis due to drugs, unspecified femur. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 217 codes in category M87 (Osteonecrosis). Its coding notes include a Use additional code instruction, 3 Excludes1 entries and 10 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

When the lower or upper end of a bone is affected near a joint, the site is the bone, not the joint.

Guidelines I.C.13.a.1Site of bone conditions: bone, not jointRead the official text

Use additional code

Add the listed code as a secondary code, if known.

Inherited from M87.1 Osteonecrosis due to drugs
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Inherited from M87 Osteonecrosis
  • code to identify major osseous defect, if applicable (M89.7-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from M87 Osteonecrosis
  • juvenile osteonecrosis (M91-M92)
  • osteochondropathies (M90-M93)
Also from chapter/block level (1 note)
Inherited from M86–M90 Other osteopathies
  • postprocedural osteopathies (M96.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 13 Diseases of the musculoskeletal system and connective tissue
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 184 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Includes

Further defines or gives examples of the content of the category.

Inherited from M87 Osteonecrosis
  • avascular necrosis of bone

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 13 Diseases of the musculoskeletal system and connective tissue
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition