M46.30

Infection of intervertebral disc (pyogenic), site unspecified

FY2027Chapter 13: Diseases of the musculoskeletal system and connective tissue/M45–M49 Spondylopathies

BillableComplete code, valid to report
Care settingsHospital CC

M46.30 (also written M4630) is a billable ICD-10-CM diagnosis code for infection of intervertebral disc (pyogenic), site unspecified. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 70 codes in category M46 (Other inflammatory spondylopathies). The Alphabetic Index lists it under 1 entry. Its coding notes include a Use additional code instruction and 10 Excludes2 entries.

Use additional code

Add the listed code as a secondary code, if known.

Inherited from M46.3 Infection of intervertebral disc
  • code (B95-B97) to identify infectious agent.

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 13 Diseases of the musculoskeletal system and connective tissue
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 221 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 13 Diseases of the musculoskeletal system and connective tissue
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry