M46.20
Osteomyelitis of vertebra, site unspecified
M46.20 (also written M4620) is a billable ICD-10-CM diagnosis code for osteomyelitis of vertebra, site unspecified. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 70 codes in category M46 (Other inflammatory spondylopathies). The Alphabetic Index lists it under 1 entry. Its coding notes include 10 Excludes2 entries.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (10 notes)
- arthropathic psoriasis (L40.5-)
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- compartment syndrome (traumatic) (T79.A-)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 221 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CIPF Comorbidity
On the CMS IPF comorbidity list.
| Comorbidity category | Factor |
|---|---|
| Severe Musculoskeletal & Connective Tissue Diseases | 1.05 |
Notes
Also from chapter/block level (1 note)
- Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 1 entry