L27.1
Localized skin eruption due to drugs and medicaments taken internally
L27.1 (also written L271) is a billable ICD-10-CM diagnosis code for localized skin eruption due to drugs and medicaments taken internally. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 5 codes in category L27 (Dermatitis due to substances taken internally). The Alphabetic Index lists it under 7 entries. Its coding notes include a Use additional code instruction, 1 Excludes1 entry and 23 Excludes2 entries.
Use additional code
Add the listed code as a secondary code, if known.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (18 notes)
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- lipomelanotic reticulosis (I89.8)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- systemic connective tissue disorders (M30-M36)
- viral warts (B07.-)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Other clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Notes
Also from chapter/block level (1 note)
- In this block the terms dermatitis and eczema are used synonymously and interchangeably.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 7 entries
- Dermatitis (eczematous), due to, drugs and medicaments (generalized) (internal use), localized skin eruption
- Eruption, drug (generalized) (taken internally), fixed
- Eruption, drug (generalized) (taken internally), localized
- Eruption, skin (nonspecific), due to inoculation/vaccination (generalized), localized
- Erythrodysesthesia, palmar plantar (PPE)
- Hand-foot syndrome
- Syndrome, hand-foot